IVFclinic in Greece

Egg freezing

Continuous advances in IVF often result in a high number of good quality embryos in each treatment cycle. Of these the embryologist will select the "best" to be transferred to the woman's body.

There is therefore a need for cryopreservation of the excess embryos that are considered suitable for this purpose.

Correspondingly, in the case of women undergoing chemotherapy / radiotherapy before childbirth or who have premature ovarian failure, severe endometriosis, ovarian cysts or wish to delay maternity, the need for cryopreservation may arise.

It is now possible: Stop your biological clock by simply putting the time in the freezer. Let's look at some of the questions you often ask at IVFclinic in Greece :

1) Which women does the egg freeze method refer to?
Egg freezing can be beneficial for a number of reasons for women who wish to maintain their fertility for the future, including:
✓ Women who wish or are forced to delay giving birth in order to fulfill personal goals.
✓ Women with a family history of early menopause.
✓ Women who are diagnosed with cancer before undergoing chemotherapy or radiation.

2) When should egg freezing take place?
The younger a woman is, the better the quality of her eggs and the greater the chances of a future pregnancy.
Ideally, it is between 28-35 years, or even earlier, in cases involving patients with cancer or other known condition with an effect on ovarian reserve.
A woman gives birth to a certain number of eggs (about 200,000-2,500,000) and decreases each month in both number and cell integrity.
Some basic laboratory fertility tests, including an ultrasound evaluation of the ovarian stocks, give a clearer picture of both the amount of eggs left in a woman and their quality.
With the help of a specialist breeding physician, Stelios Papadopoulos, the results are evaluated so each woman can choose the appropriate time to perform the procedure.

3) How does egg freezing work? The cryopreservation of the eggs / embryos is performed by the vitrification method. During hatching the eggs / embryos are exposed to a small volume of cryoprotectant fluid, which protects them from the stress caused by the rapid drop in temperature to -196 ° C. The eggs / embryos are then stored in liquid nitrogen containers where they can remain until used in a future cycle.
4) What procedure is followed for freezing the eggs?

In order to collect the eggs for freezing, the woman undergoes the same process of ovarian stimulation with the use of hormonal preparations, as in an IVF attempt. The only difference is that, after the egg is hatched, the eggs are not fertilized by the sperm, nor is embryo transfer. The eggs are cryopreserved until the ganika demands fertilization.
The total duration of the procedure is approximately 9-12 days, during which injections are made for multiple egg production. Once the eggs have matured sufficiently, they are removed with a needle placed through the vagina under ultrasound guidance. This procedure is done under intravenous doping and is not painful. The eggs are then frozen immediately. When the woman is ready to attempt a pregnancy, the eggs are thawed and fertilized by the sperm and then the embryos formed are transferred to the patient's womb by a painless procedure called embryo transfer.

5) How long can the eggs remain frozen?
Based on scientific data and the experience of vitrification in the last 10 years, the storage of frozen eggs does not lead to any decrease in quality.

6) How many eggs must be cryopreserved to achieve a pregnancy?
According to scientific studies, in women up to 38 years of age, the survival rate of eggs after thawing is 75%, as is the fertilization rate. Thus, if a woman has 10 eggs frozen, 7 are expected to survive defrost and 5 to 6 are expected to fertilize and become embryos. Usually 2 embryos are transferred to women up to 38 years of age.

7) Is egg freezing safe?
To date, approximately 6,000 babies have been born with frozen eggs. The largest study published with more than 900 babies from frozen eggs showed no increased rate of genetic abnormalities compared to the general population, nor increased rates of chromosomal abnormalities compared to embryos derived from "fresh" eggs. In 2014, a new study showed that complications during pregnancy after thawing did not increase.
All of the above are reassuring and more and more studies are being done as the need for cryopreservation of the eggs is constantly increasing.
Dr.Stelios Papadopoulos, MD, DFFP, BSCCP
Contact Person

Dr. Stelios Papadopoulos, MD, DFFP, BSCCP

(+30) 697 588 3030 - This email address is being protected from spambots. You need JavaScript enabled to view it.

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